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CAUSA: 基于密码子-氨基酸联合序列比对构建高精确度分子进化树 生物信息学、基因组学(包括功能基因组学和比较基因组学)的主要目的是研究生物基因、蛋白和基因组的结构和功能,并重构生物基因、蛋白和基因组的进化历史。多序列比对(multiple sequence alignment, MSA)是DNA和蛋白质分子进化分析、以及结构与功能研究的基本工具。目前多序列比对已经有很多方法,如clustalw, MUSCLE, MAFFT, T-Coffee, PRANK,等等,但序列比对依然容易产生系统性
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ProDA is public domain software for multiple alignment of protein sequences with repeated and shuffled elements
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该软件是一款用来对核酸与蛋白序列进行多序列比对,也可用来发现特征序列,进行蛋白分类。-The software is a multiple sequence alignment for nucleic acid and protein sequences ,and also can be used to detect the characteristic sequence of protein classification.
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DNA sequence alignment is the most
commonly application in computational biology. It is
essential pre-requisite of many other operations in
computational biology applications. Optimal alignment
for a large scale size DNA sequence dataset is a
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Multiple alignment of nucleic acid and protein sequences
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